Recent studies have also demonstrated the benefits of early glucocorticoid treatment, before significant physical decline.1-3
Preserved muscle strength and motor function4,5
Delayed loss of ambulation1,4
Preserved pulmonary function1,4,5
Avoidance of scoliosis surgery1,4,5
*compared to untreated patients
The 2018 International Care Guidelines recommends following an initial consultation with the family, a discussion regarding side effects and a nutritional consultation should occur before any glucocorticoid treatment is initiated.1 Well documented side effects of long-term corticosteroid use can include; weight gain and obesity, acne and warts, cushingoid features, growth retardation and delayed puberty, cataracts, immune/adrenal suppression, glucose intolerance, hypertension, adverse behavioural changes, gastro-oesophageal reflux, peptic ulcer, gastritis, osteoporosis and myoglobinuria.6
Click here for the International Duchenne Care Considerations summaries.
(excluding UK and Ireland)
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