red flags
Children demonstrating red flag signs and symptoms such as significant development delay could have Duchenne muscular dystrophy
Birnkrant DJ, et al. Lancet Neurol. 2018;17:251–267.
National Task Force for Early Identification of Childhood Neuromuscular Disorders. Guide for primary care providers. Available at: https://childmuscleweakness.org/wp-content/uploads/2019/05/PrimaryCareProviderPacket.pdf [last accessed November 2020].
genetic counselling
Genetic counselling offers many benefits for families living with Duchenne muscular dystrophy
Helderman-van den Enden AT, et al. Clin Genet. 2011;79:236–242
GPs are the first point of contact
GPs are a first point of contact for concerned parents and they can be a driving force behind a successful diagnostic journey
Birnkrant DJ, et al. Lancet Neurol. 2018;17:445–455.
Noritz GH, et al. Pediatrics. 2013;131:e2016–e2027.
second birthday
Early signs and symptoms of Duchenne muscular dystrophy may appear before a child’s second birthday
rare genetic disorder
Duchenne muscular dystrophy is a rare genetic disorder that causes progressive muscular damage and degeneration
Van Ruiten HJ, et al. Arch Dis Child. 2014;99:1074–1077. 2. Birnkrant DJ, et al. Lancet Neurol. 2018;17:251–267.
most common and severe forms
Duchenne muscular dystrophy is one of the most common and severe forms of muscular dystrophy
National Institutes of Health. Muscular dystrophy. Available at: https://www.nichd.nih.gov/health/topics/factsheets/540 [last accessed November 2020].
Van Ruiten HJ, et al. Arch Dis Child. 2014;99:1074–1077.
Acurate and early diagnosis
Duchenne muscular dystrophy is a progressive disease that presents in early childhood and requires an accurate and early diagnosis to avoid life-threatening complications
Birnkrant DJ, et al. Lancet Neurol. 2018;17:251–267.
genetic testing
Genetic testing can confirm Duchenne muscular dystrophy
Birnkrant DJ, et al. Lancet Neurol. 2018;17(3):251–267.
Aartsma-Rus A, et al. J Med Genet. 2016;53(3):145–151
It is estimated that about 20,000 children are diagnosed with Duchenne globally each year.
It is estimated that about 20,000 children are diagnosed with Duchenne globally each year.
The most common forms in children, Duchenne and Becker, affect approximately 1 in every 5,600 to 7,700 males ages 5 to 24
The most common forms in children, Duchenne and Becker, affect approximately 1 in every 5,600 to 7,700 males ages 5 to 24
Most Common
Duchenne muscular dystrophy is the most common fatal genetic disorder in children affecting ~1 out of every 3,600–6,000 live male births